The Interaction of Platelets With Aortic Subendothelium : Inhibition of Adhesion and Secretion by Prostaglandin 12
نویسنده
چکیده
We have studied the effect of prostaglandin I2 on platelet turnover, attachment to the subendothelium, and secretion following balloon deendothelialization of the rabbit aorta. Survival of 51Cr-labeled platelets in the balloon-injured animals remained normal. Thirty minutes after injury. there were 4.52 x 1O platelets/sq cm attached to the aortic surface. which was 87% covered by platelets. Although plasma platelet factor 4. as measured by radioimmunoassay, did not rise above the normal level of 6.8 ± 2.6 ng/ml (mean ± SEM) during the first hour after balloon injury. platelet factor 4 antigen was detected within the vessel wall by indirect immunofluorescence
منابع مشابه
The Interaction of Platelets With Aortic Subendothelium : Inhibition of Adhesion and Secretion by Prostaglandin 12
We have studied the effect of prostaglandin I2 on platelet turnover, attachment to the subendothelium, and secretion following balloon deendothelialization of the rabbit aorta. Survival of 51Cr-labeled platelets in the balloon-injured animals remained normal. Thirty minutes after injury. there were 4.52 x 1O platelets/sq cm attached to the aortic surface. which was 87% covered by platelets. Alt...
متن کاملThe interaction of platelets with aortic subendothelium: inhibition of adhesion and secretion by prostaglandin I2.
We have studied the effect of prostaglandin I2 on platelet turnover, attachment to the subendothelium, and secretion following balloon deendothelialization of the rabbit aorta. Survival of 51Cr-labeled platelets in the balloon-injured animals remained normal. Thirty minutes after injury, there were 4.52 X 10(6) platelets/sq cm attached to the aortic surface, which was 87% covered by platelets. ...
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تاریخ انتشار 2005